Jagtap A G, Karkera S G
Department of Pharmacology, Bombay College of Pharmacy, Santacruz (E), Mumbai, India.
J Ethnopharmacol. 1999 Dec 15;68(1-3):299-306. doi: 10.1016/s0378-8741(99)00058-6.
The aqueous extract from Terminalia chebula was tested for its ability to inhibit the growth and some physiological functions of Streptococcus mutans. The extract strongly inhibited the growth, sucrose induced adherence and glucan induced aggregation of S. mutans. Mouthrinsing with a 10% solution of the extract inhibited the salivary bacterial count and salivary glycolysis. Mouthrinsing with the extract significantly reduced total bacterial counts and the total streptococcal counts in the saliva samples obtained up to and including 3 h after rinsing, compared with the counts obtained prerinsing or after placebo rinsing. The extract successfully inhibited glycolysis of salivary bacteria for up to 90 min postrinsing.
对诃子的水提取物进行了测试，以检验其抑制变形链球菌生长及某些生理功能的能力。该提取物强烈抑制变形链球菌的生长、蔗糖诱导的黏附以及葡聚糖诱导的聚集。用10%的提取物溶液漱口可抑制唾液细菌计数和唾液糖酵解。与漱口前或用安慰剂漱口后获得的计数相比，用该提取物漱口可显著降低直至漱口后3小时（包括3小时）采集的唾液样本中的总细菌计数和总链球菌计数。该提取物在漱口后长达90分钟内成功抑制了唾液细菌的糖酵解。
