Chiang-Salgado M T, Casanueva-Escobar V, Cid-Cea X, González-Rubilar U, Olate-Mellado P, Nickel-Paredes F, Revello-Chiang L
Departamento de Fisiopatología, Facultad de Ciencias Biológicas, Universidad de Concepción, Chile.
Salud Publica Mex. 1999 Nov-Dec;41(6):444-51.
To study the prevalence of cardiovascular risk factors in asymptomatic university students of both sexes, aged 18 to 25 years.
Serum lipid levels were measured in a subsample of 293 subjects, using a Hitachi 717 chemical analyzer. Obesity was classified using body mass index (BMI) measurements. A self-applied questionnaire was used to collect data on sedentary life style, family history of cardiovascular disease and cigarette smoking. Statistical associations of lipid levels with lipidic and non-lipidic risk factors were assessed using Pearson's chi-square test and multiple regression.
We found lipid risk levels in 29.2% for total cholesterol (CT), 16.2% for low-density lipoproteins (C-LDL) and 5% for high-density lipoproteins (C-HDL). The main non-lipidic factors were smoking (46.1%) and sedentarism (60.8%). Obesity, hypertension and parental history of myocardial infarction were present in 1.9%, 4.6% and 11%, respectively. We observed an association of a lipid risk profile with obesity, cigarette smoking and family history.
The results show that sedentarism and smoking are associated with a lipid risk profile. These results call for the need to develop appropriate behavior strategies for the successful prevention of cardiovascular disease.
研究18至25岁无症状男女大学生心血管危险因素的患病率。
使用日立717化学分析仪对293名受试者的子样本进行血脂水平测量。采用体重指数（BMI）测量对肥胖进行分类。通过自行填写的问卷收集有关久坐生活方式、心血管疾病家族史和吸烟情况的数据。使用Pearson卡方检验和多元回归评估血脂水平与脂质和非脂质危险因素之间的统计关联。
我们发现总胆固醇（CT）的脂质风险水平为29.2%，低密度脂蛋白（C-LDL）为16.2%，高密度脂蛋白（C-HDL）为5%。主要的非脂质因素是吸烟（46.1%）和久坐不动（60.8%）。肥胖、高血压和心肌梗死家族史的发生率分别为1.9%、4.6%和11%。我们观察到脂质风险状况与肥胖、吸烟和家族史之间存在关联。
结果表明，久坐不动和吸烟与脂质风险状况有关。这些结果表明需要制定适当的行为策略以成功预防心血管疾病。
