Liu C J, Chiou H J, Chiang S C, Chou J C, Chou Y H, Liu J H
Department of Ophthalmology, Veterans General Hospital-Taipei, Taiwan.
Acta Ophthalmol Scand. 1999 Dec;77(6):658-62. doi: 10.1034/j.1600-0420.1999.770610.x.
To determine the retrobulbar hemodynamics in glaucoma patients with different degrees of optic nerve damage.
Color Doppler imaging was performed in 52 patients with controlled primary open angle glaucoma (POAG) and in 25 control subjects. Glaucomatous eyes were divided into early and late groups based on the perimetry findings. Peak systolic velocity (PSV), end diastolic velocity (EDV), and resistive index of the central retinal artery (CRA) and posterior ciliary arteries (PCA) were evaluated.
Early glaucoma showed significantly decreased PSV in nasal PCA when compared with the normal. Late glaucoma showed significantly decreased PSV and EDV in the CRA and nasal PCA, and significantly decreased PSV in temporal PCA as compared with the control and early glaucoma. The resistive index of the CRA also increased significantly in late glaucoma.
Eyes with advanced glaucomatous optic neuropathy were associated with more marked alterations in retrobulbar circulation than eyes with less nerve damage.
确定不同程度视神经损伤的青光眼患者的球后血流动力学情况。
对52例原发性开角型青光眼（POAG）病情得到控制的患者及25名对照者进行彩色多普勒成像检查。根据视野检查结果将青光眼患眼分为早期和晚期组。评估视网膜中央动脉（CRA）和睫状后动脉（PCA）的收缩期峰值流速（PSV）、舒张末期流速（EDV）及阻力指数。
与正常情况相比，早期青光眼患者鼻侧PCA的PSV显著降低。与对照组及早期青光眼相比，晚期青光眼患者CRA和鼻侧PCA的PSV及EDV显著降低，颞侧PCA的PSV显著降低。晚期青光眼患者CRA的阻力指数也显著升高。
与神经损伤较轻的患眼相比，晚期青光眼性视神经病变患眼的球后循环改变更为明显。
