Detorakis Efstathios T, Achtaropoulos Athanassios K, Drakonaki Eleni E, Kozobolis Vassilios P
Department of Ophthalmology, Democritus University of Thrace, Alexandroupolis, Greece.
Graefes Arch Clin Exp Ophthalmol. 2007 Apr;245(4):516-21. doi: 10.1007/s00417-006-0439-7. Epub 2006 Nov 17.
Previous studies have reported impaired blood flow in the ophthalmic artery (OA) and central retinal artery (CRA) in exfoliation syndrome and exfoliation glaucoma. This study evaluates blood flow at the long and short posterior ciliary arteries (LPCA and SPCA, respectively) in these conditions.
Consecutively examined candidates for cataract surgery were included. Only one eye (OD) was included in the analyses for consistency. Patients were classified into non-glaucoma and non-exfoliation (controls), primary open angle glaucoma (POAG), exfoliation syndrome and exfoliation glaucoma groups, based on the findings of the OD. Sixty-eight patients (41 males, 60.3%) were included. Color Doppler imaging (CDI) of the nasal and temporal branches of LPCA and SPCA was performed using a 7.5 Mhz probe. The peak systolic velocity (PSV), end diastolic velocity (EDV) and resistivity index (RI) were recorded for the examined vessels.
EDV at the LPCA was significantly lower in exfoliation syndrome and glaucoma, compared with controls and POAG respectively. EDV was significantly lower and RI was significantly higher at the SPCA in exfoliation glaucoma, compared with exfoliation, whereas respective differences were statistically not significant between controls and POAG.
The hemodynamic impairment at the LPCA in exfoliation syndrome and glaucoma supports an association between exfoliation and ischemic stress at the anterior ocular segment.
既往研究报道过剥脱综合征和剥脱性青光眼患者眼动脉（OA）及视网膜中央动脉（CRA）血流受损。本研究评估这些情况下的睫状后长动脉和睫状后短动脉（分别为LPCA和SPCA）的血流情况。
纳入连续接受白内障手术检查的患者。为保持一致性，分析仅纳入一只眼（右眼）。根据右眼检查结果，将患者分为非青光眼且无剥脱（对照组）、原发性开角型青光眼（POAG）、剥脱综合征和剥脱性青光眼组。共纳入68例患者（41例男性，占60.3%）。使用7.5Mhz探头对LPCA和SPCA的鼻侧和颞侧分支进行彩色多普勒成像（CDI）。记录检查血管的收缩期峰值流速（PSV）、舒张末期流速（EDV）和阻力指数（RI）。
与对照组和POAG相比，剥脱综合征和青光眼患者LPCA的EDV分别显著降低。与剥脱综合征相比，剥脱性青光眼患者SPCA的EDV显著降低且RI显著升高，而对照组和POAG之间的相应差异无统计学意义。
剥脱综合征和青光眼患者LPCA的血流动力学损害支持剥脱与眼前节缺血应激之间存在关联。
