Pandey M R
Mrigendra Samjhana Medical Trust.
J Indian Med Assoc. 1999 Sep;97(9):367-9.
Coronary artery diseases is rapidly increasing in our part of the world. The South Asian ethnic groups are especially vulnerable to coronary artery disease. The two most striking features of coronary artery disease in the South Asian population are extreme prematurity and severity of the disease, both resulting from the malignant atherosclerosis that begins at an earlier age than in other population. Triple vessel disease and complicated lesions are not common even in young people and follow a malignant course. The most important aspect of prevention is to identify individuals with high risk of coronary artery disease at an early age and aggressive modification of risk factors. Tobacco smoking and hypertension are the two most important risk factors for coronary heart disease and stroke. Both of these risk factors have very high prevalence in India, Nepal and other countries of this region. There is a synergistic interaction of tobacco smoking with hypertension and high blood cholesterol which greatly increase coronary heart disease risk as well as sudden death and stroke.
在我们所在的地区，冠状动脉疾病正在迅速增加。南亚族裔群体尤其容易患冠状动脉疾病。南亚人群中冠状动脉疾病最显著的两个特征是疾病的极端早熟和严重性，这两者都是由比其他人群更早开始的恶性动脉粥样硬化导致的。即使在年轻人中，三支血管病变和复杂病变也不常见，并且病情呈恶性发展。预防的最重要方面是在早年识别出患冠状动脉疾病风险高的个体，并积极改变危险因素。吸烟和高血压是冠心病和中风的两个最重要危险因素。这两个危险因素在印度、尼泊尔和该地区的其他国家都有很高的患病率。吸烟与高血压和高胆固醇血症之间存在协同相互作用，这大大增加了冠心病风险以及猝死和中风的风险。
