Gooding D C, Kwapil T R, Tallent K A
Department of Psychology, University of Wisconsin-Madison 53706-1696, USA.
Schizophr Res. 1999 Dec 21;40(3):201-9. doi: 10.1016/s0920-9964(99)00124-3.
The present study investigates executive functioning in schizotypic college students and control subjects using the Wisconsin Card Sorting Test (WCST). Inhibitory control and working memory, two aspects of executive functioning, were examined in deviantly high scorers on the Perceptual Aberration and Magical Ideation Scales (n=97), high scorers on the revised Social Anhedonia Scale (n=58), and in control subjects (n=104). The schizotypic groups displayed significantly more perseverative errors and achieved fewer categories than the control group. The two schizotypic groups did not differ from each other. We identified a subset of schizotypic individuals who also produced clinically deviant WCST profiles. The findings support the hypothesis that executive function deficits may precede the onset of schizophrenia and related illnesses.
本研究使用威斯康星卡片分类测验(WCST)调查了分裂型人格特质的大学生和对照受试者的执行功能。在知觉偏差和神奇观念量表得分异常高的受试者(n = 97)、修订版社交快感缺乏量表得分高的受试者(n = 58)以及对照受试者(n = 104)中,对执行功能的两个方面,即抑制控制和工作记忆进行了检查。与对照组相比,分裂型人格特质组表现出显著更多的持续性错误,且分类数更少。两个分裂型人格特质组之间没有差异。我们确定了一部分分裂型人格特质个体,他们在WCST测试中也表现出临床异常的结果。这些发现支持了执行功能缺陷可能先于精神分裂症及相关疾病发作的假说。