致命性心肌再灌注损伤：它是否存在，我们是否应该对其进行治疗？ - Suppr

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超能文献

Lethal Myocardial Reperfusion Injury: Does it Exist, Should We Treat It?

作者信息

Ambrosio G, Tritto I

机构信息

Division of Cardiology. University of Perugia School of Medicine, Perugia, Italy.

出版信息

J Thromb Thrombolysis. 1997 Jan;4(1):69-70. doi: 10.1023/a:1017554619252.

DOI:10.1023/a:1017554619252

PMID:10639229

Abstract

摘要

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Lethal myocardial reperfusion injury: a necessary evil?致命性心肌再灌注损伤：必要之恶？

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Pre-conditioning and postconditioning to limit ischemia-reperfusion-induced myocardial injury: what could be the next footstep?限制缺血再灌注诱导的心肌损伤的预处理和后处理：下一步可能是什么？

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Carvedilol improves function and reduces infarct size in the feline myocardium by protecting against lethal reperfusion injury.卡维地洛通过预防致死性再灌注损伤来改善猫心肌的功能并减小梗死面积。

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本文引用的文献

Modulation of platelet function by reactive oxygen metabolites.活性氧代谢产物对血小板功能的调节

Am J Physiol. 1994 Jul;267(1 Pt 2):H308-18. doi: 10.1152/ajpheart.1994.267.1.H308.

Superoxide radical: controversies, contradictions, and paradoxes.超氧阴离子自由基：争议、矛盾与悖论

Proc Soc Exp Biol Med. 1995 Jun;209(2):112-7. doi: 10.3181/00379727-209-43885c.

The role of oxygen free radicals in preconditioning.

J Mol Cell Cardiol. 1995 Apr;27(4):1035-9. doi: 10.1016/0022-2828(95)90072-1.

Reduction in experimental infarct size by recombinant human superoxide dismutase: insights into the pathophysiology of reperfusion injury.重组人超氧化物歧化酶对实验性梗死面积的缩小作用：对再灌注损伤病理生理学的见解

Circulation. 1986 Dec;74(6):1424-33. doi: 10.1161/01.cir.74.6.1424.

Free radicals and myocardial ischemia and reperfusion injury.自由基与心肌缺血再灌注损伤

J Lab Clin Med. 1987 Jul;110(1):13-30.

"Reperfusion injury" by oxygen-derived free radicals? Effect of superoxide dismutase plus catalase, given at the time of reperfusion, on myocardial infarct size, contractile function, coronary microvasculature, and regional myocardial blood flow.氧衍生自由基导致的“再灌注损伤”？再灌注时给予超氧化物歧化酶加过氧化氢酶对心肌梗死面积、收缩功能、冠状动脉微血管及局部心肌血流的影响。

Circ Res. 1989 Jan;64(1):86-96. doi: 10.1161/01.res.64.1.86.

The role of neutrophils and free radicals in the ischemic-reperfused heart: why the confusion and controversy?中性粒细胞和自由基在缺血再灌注心脏中的作用：为何存在混淆和争议？

J Mol Cell Cardiol. 1989 Dec;21(12):1225-39. doi: 10.1016/0022-2828(89)90669-x.

Can superoxide dismutase alter myocardial infarct size?超氧化物歧化酶能改变心肌梗死面积吗？

Circulation. 1989 May;79(5):1137-42. doi: 10.1161/01.cir.79.5.1137.

Reperfusion injury and its pharmacologic modification.再灌注损伤及其药物修饰

Circulation. 1989 Oct;80(4):1049-62. doi: 10.1161/01.cir.80.4.1049.

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