Ubel P A, Richardson J, Prades J L
University of Pennsylvania, USA.
Int J Technol Assess Health Care. 1999 Fall;15(4):738-48.
Decision-makers and the general public are often reluctant to adopt policy recommendations based exclusively upon cost-utility analyses. One possible reason explored here is that patients' previous health state before experiencing the onset of an acute life-threatening illness may influence the value of saving those patients' lives.
We surveyed members of the general public to see the relative importance of saving patients' lives when some patients could be returned to perfect health and others would live the remainder of their years with paraplegia. Among this latter group, some were described as having pre-existing paraplegia. Others were described as having as having the onset of paraplegia. The relative importance of saving each of these lives was measured using the person trade-off method.
Six hundred five subjects completed questionnaires, and 250 met pre-established consistency criteria and were included in the final analysis. Overall, subjects placed equal importance on saving the lives of people with pre-existing paraplegia versus those who could be returned to perfect health because they did not have pre-existing paraplegia. In contrast, respondents gave lower priority to patients who would experience the onset of paraplegia after having their lives saved, especially if their paraplegia was avoidable with an alternative treatment.
People do not think that all quality-adjusted life-years are created equal. Instead, the value that people place on treatment programs depends on patients' state of health before developing life-threatening illnesses, and on whether alternative treatments are available that provide better health outcomes for the patients. These results may explain, in part, public discomfort over basing health care priorities on cost-utility analysis.
决策者和普通大众通常不愿仅基于成本效用分析来采纳政策建议。本文探讨的一个可能原因是,患者在经历危及生命的急性疾病发作之前的健康状况,可能会影响挽救这些患者生命的价值。
我们对普通大众进行了调查,以了解在一些患者能够恢复到完全健康状态而另一些患者将在截瘫状态下度过余生时,挽救患者生命的相对重要性。在后一组患者中,一些被描述为患有先天性截瘫,另一些则被描述为截瘫刚刚发作。使用个人权衡法来衡量挽救这些生命的相对重要性。
605名受试者完成了问卷调查,250名符合预先设定的一致性标准并被纳入最终分析。总体而言,受试者认为挽救患有先天性截瘫的人与挽救那些因没有先天性截瘫而能够恢复到完全健康状态的人的生命同等重要。相比之下,受访者对那些在被挽救生命后会出现截瘫的患者给予较低的优先级,尤其是如果他们的截瘫可以通过替代治疗避免的话。
人们并不认为所有的质量调整生命年都是等同的。相反,人们对治疗方案的重视程度取决于患者在患上危及生命的疾病之前的健康状况,以及是否有替代治疗方法可以为患者带来更好的健康结果。这些结果可能部分解释了公众对将医疗保健优先级基于成本效用分析的不满。