[用于诊断目的的聚丙烯酰胺与寡核苷酸及其模拟物的缀合物]
[Conjugates of polyacrylamide with oligonucleotides and their mimetics for diagnostic purposes].
作者信息
Efimov V A, Chakhmakhcheva O G
机构信息
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
出版信息
Bioorg Khim. 1999 Nov;25(11):848-54.
PMID:10645490
Abstract
Approaches to preparing acrylamide and polyacrylamide conjugates with oligonucleotides and some peptide nucleic acid-related DNA mimics are considered. Their physicochemical properties and application to the nucleic acid analysis are discussed.
摘要
本文考虑了制备丙烯酰胺和聚丙烯酰胺与寡核苷酸及一些与肽核酸相关的DNA模拟物的缀合物的方法。讨论了它们的物理化学性质及其在核酸分析中的应用。
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