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通过SF36健康调查问卷评估前庭神经鞘瘤患者术后的生活质量。

Postoperative quality of life in vestibular schwannoma patients measured by the SF36 Health Questionnaire.

作者信息

da Cruz M J, Moffat D A, Hardy D G

机构信息

Department of Otoneurosurgical and Skull Base Surgery, Addenbrooke's Hospital, Cambridge.

出版信息

Laryngoscope. 2000 Jan;110(1):151-5. doi: 10.1097/00005537-200001000-00027.

Abstract

OBJECTIVE

To quantify the postoperative quality of life in patients following surgical treatment for vestibular schwannoma.

STUDY DESIGN

Patient self-assessment using the short form 36 (SF36) multidimensional quality of life health questionnaire. Sex- and age-matched normalized scores were calculated using a standardized process and accepted normative data.

SETTING

Tertiary referral skull base unit.

RESULTS

An 80% response rate (90 patients) was achieved. The postoperative quality of life in vestibular schwannoma patients, as quantified by seven of the eight SF36 health scales was less than the appropriate matched healthy standard. Comparison of a variety of preoperative patients and tumor factors-different operative approaches (translabyrinthine and retrosigmoid), tumor size (group cut of points of tumor diameter 1.5 mm and 2.5 mm), patient sex, and ranking of patient age-showed no statistically significant difference in measured quality of life outcomes for each of these traditional predictors.

CONCLUSION

Reduced quality of life in patients after surgical treatment for vestibular schwannoma, coupled with the low tumor growth rates and minimal preoperative symptoms, supports a conservative approach to patient management. The advantages and disadvantages of a variety of approaches used to measure the quality of life after surgical treatment of vestibular schwannoma and their impact on clinical decision making for patients, are discussed.

摘要

目的

量化前庭神经鞘瘤手术治疗患者的术后生活质量。

研究设计

使用简短健康调查问卷36项(SF36)进行患者自我评估。采用标准化流程和公认的标准数据计算性别和年龄匹配的标准化分数。

研究地点

三级转诊颅底科室。

结果

应答率为80%(90例患者)。通过SF36健康量表中的七项量表量化,前庭神经鞘瘤患者的术后生活质量低于相应匹配的健康标准。比较各种术前患者和肿瘤因素——不同手术入路(迷路后入路和乙状窦后入路)、肿瘤大小(肿瘤直径1.5毫米和2.5毫米的分组切点)、患者性别以及患者年龄排名——结果显示,这些传统预测因素中,每一项在测量的生活质量结果方面均无统计学显著差异。

结论

前庭神经鞘瘤手术治疗后患者生活质量下降,再加上肿瘤生长速度低和术前症状轻微,支持对患者采取保守治疗方法。讨论了用于测量前庭神经鞘瘤手术治疗后生活质量的各种方法的优缺点及其对患者临床决策的影响。

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