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单侧前庭神经鞘瘤显微手术、放射外科手术及保守治疗后的生活质量。

Quality of life following microsurgery, radiosurgery and conservative management for unilateral vestibular schwannoma.

作者信息

Sandooram D, Grunfeld E A, McKinney C, Gleeson M J

机构信息

Department of Otolaryngology, Guy's & St Thomas' Hospital, London, UK.

出版信息

Clin Otolaryngol Allied Sci. 2004 Dec;29(6):621-7. doi: 10.1111/j.1365-2273.2004.00881.x.

Abstract

The best way to manage small and medium-sized vestibular schwannomas is currently a matter of heated debate. As these tumours are not immediately life-threatening, patients are invariably concerned about how management would affect their quality of life. Until now, no study has compared the three treatment modalities in terms of physical, psychological and social wellbeing. This study is based on a retrospective database analysis and postal questionnaire survey of unilateral vestibular schwannoma patients who had either been managed conservatively, or treated with microsurgery or radiosurgery. The results showed that: quality of life (measured by the Glasgow Benefit Inventory) deteriorated after microsurgery, particularly for small tumours; conservative management did not lead to a change in quality of life, and there was a trend towards poorer quality of life following radiosurgery. The findings suggest that a conservative management approach may be more appropriate for small tumours, and that patients who are due to undergo microsurgery or radiosurgery may benefit from counselling about the potential impact of treatment on quality of life.

摘要

目前,如何管理中小型前庭神经鞘瘤是一个激烈争论的问题。由于这些肿瘤不会立即危及生命,患者总是担心治疗会如何影响他们的生活质量。到目前为止,尚无研究在身体、心理和社会福祉方面对三种治疗方式进行比较。本研究基于对单侧前庭神经鞘瘤患者的回顾性数据库分析和邮寄问卷调查,这些患者要么接受了保守治疗,要么接受了显微手术或放射外科治疗。结果显示:显微手术后生活质量(通过格拉斯哥获益量表衡量)下降,尤其是对于小肿瘤;保守治疗未导致生活质量改变,而放射外科治疗后生活质量有变差的趋势。研究结果表明,对于小肿瘤,保守治疗方法可能更合适,并且即将接受显微手术或放射外科治疗的患者可能会从关于治疗对生活质量潜在影响的咨询中受益。

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