Neale T J, Lynn K L, Bailey R R
N Z Med J. 1976 Mar 10;83(559):147-9.
Five patients in whom deterioration in renal function was associated with the use of the aldosterone antagonist, spironolactone, are reported. Care in the use of this drug is urged, especially in the elderly. Patients with known renal functional impairment should not receive this agent.
报告了5例肾功能恶化与使用醛固酮拮抗剂螺内酯有关的患者。强烈建议谨慎使用该药物,尤其是在老年人中。已知有肾功能损害的患者不应使用此药。