Sasaki T, Ohsawa S, Ogawa M, Mukaida M, Nakajima T, Komoda K, Tachieda R, Niinuma H, Kawazoe K
Third Department of Surgery, Iwate Medical University, Morioka, Japan.
Surg Today. 2000;30(1):33-6. doi: 10.1007/PL00010043.
We describe herein the postoperative renal functions of patients who required a suprarenal aortic cross-clamp during abdominal aortic surgery. Seven patients required a unilateral suprarenal aortic cross-clamp (group A) and six patients required a bilateral suprarenal clamp (group B). Eighty-three patients who required an infrarenal aortic clamp were assigned to group C. Renal hypothermia with renal perfusion or topical cooling during suprarenal clamp was not performed. No hospital deaths were encountered. In group B, the postoperative creatinine and blood urea nitrogen (BUN) levels remained statistically significantly higher than that of group C until the seventh postoperative day. The postoperative renal dysfunction (serum creatinine level >2.0 mg/dl) was 28.6% in group A and 50% in group B, while it was only 8.4% in group C, although no patient required either temporary or permanent hemodialysis. The postoperative peak BUN over 30 min suprarenal clamp was significantly higher than that within 30 min. In summary, the postoperative renal function was impaired after an extended bilateral suprarenal clamp. These findings suggest that if prolonged renal ischemia is thus expected, then renal preservation should be considered.
我们在此描述了在腹主动脉手术期间需要进行肾上主动脉交叉钳夹的患者的术后肾功能。7例患者需要单侧肾上主动脉交叉钳夹(A组),6例患者需要双侧肾上钳夹(B组)。83例需要肾下主动脉钳夹的患者被分配到C组。在肾上钳夹期间未进行肾低温灌注或局部降温。未发生医院死亡病例。在B组中,术后肌酐和血尿素氮(BUN)水平在术后第7天之前一直显著高于C组。术后肾功能不全(血清肌酐水平>2.0 mg/dl)在A组为28.6%,在B组为50%,而在C组仅为8.4%,尽管没有患者需要临时或永久性血液透析。肾上钳夹超过30分钟后的术后BUN峰值显著高于30分钟内的峰值。总之,双侧肾上钳夹时间延长后术后肾功能受损。这些发现表明,如果预计会出现长时间的肾缺血,那么应考虑肾脏保护。