Kudo Fabio A, Nishibe Toshiya, Miyazaki Keiko, Murashita Toshifumi, Yasuda Keishu, Ando Motomi, Nishibe Masayasu
Department of Cardiovascular Surgery, Hokkaido University School of Medicine, Sapporo, Japan.
Surg Today. 2004;34(12):1010-3. doi: 10.1007/s00595-004-2871-9.
To examine postoperative renal function after suprarenal aortic cross-clamping performed without renal hypothermia in patients undergoing elective abdominal aortic aneurysm (AAA) surgery.
Between 1991 and 2000, 18 patients underwent surgery for a juxtarenal AAA, which required a suprarenal aortic cross-clamp. All AAAs were repaired with a proximal anastomosis just below the renal arteries. We divided the patients into two groups according to the duration of the renal ischemia: <45 min (n = 12) and > or =45 min (n = 6). The postoperative changes in renal function were analyzed.
There were no hospital deaths and none of the patients needed permanent hemodialysis. The postoperative peak in the serum creatinine level after suprarenal cross-clamping for > or =45 min was significantly higher than that after cross-clamping for <45 min. The percentage changes in serum creatinine and blood urea nitrogen were correlated positively with the duration of renal ischemia, and were significantly greater in the group with renal ischemia of <45 min than in the group with prolonged renal ischemia (> or =45 min).
Suprarenal aortic cross-clamp without performing renal hypothermia is safe and able to be tolerated well by the patient during elective AAA surgery, although careful attention must be paid to limiting the period of renal ischemia.
研究在接受择期腹主动脉瘤(AAA)手术的患者中,在不进行肾低温的情况下进行肾上腹主动脉交叉钳夹术后的肾功能。
1991年至2000年间,18例患者接受了近肾型AAA手术,该手术需要进行肾上腹主动脉交叉钳夹。所有AAA均通过在肾动脉下方进行近端吻合来修复。我们根据肾缺血持续时间将患者分为两组:<45分钟(n = 12)和≥45分钟(n = 6)。分析术后肾功能的变化。
无住院死亡病例,且无一例患者需要永久性血液透析。肾上交叉钳夹≥45分钟后的血清肌酐水平术后峰值显著高于<45分钟后的峰值。血清肌酐和血尿素氮的百分比变化与肾缺血持续时间呈正相关,且肾缺血<45分钟组的变化显著大于肾缺血延长组(≥45分钟)。
在择期AAA手术期间,不进行肾低温的肾上腹主动脉交叉钳夹是安全的,患者能够很好地耐受,尽管必须注意限制肾缺血时间。