Furedi A
British Pregnancy Advisory Service, Solihull, West Midlands, UK.
Hum Reprod Update. 1999 Nov-Dec;5(6):621-6. doi: 10.1093/humupd/5.6.621.
The warning issued by the UK Committee on Safety Medicines in October 1995, followed by their 'Dear Doctor' letter of October 18, 1995, that oral contraceptive pills containing gestodene or desogestrel were associated with a higher risk of venous thromboembolism has had a negative impact on public heath. A significant number of women either switched brands or ceased contraception altogether following the announcement. National data suggest a strong association between the pill scare and a substantial increase in the number of unintended pregnancies, particularly significant among younger women, with use of oral contraception falling from 40 to 27% of under 16s between 1995-1996 and 1996-1997. The resulting cost of the increase in births and abortions to the National Health Service has been estimated at about Pound Sterling 21 million for maternity care and from Pound Sterling 46 million for abortion provision. The level of risk should, in future, be more carefully assessed and advice more carefully presented in the interests of public health.
英国药品安全委员会于1995年10月发布警告,并于1995年10月18日发出“致医生函”,指出含有孕二烯酮或去氧孕烯的口服避孕药与静脉血栓栓塞风险较高有关,这对公众健康产生了负面影响。公告发布后,大量女性要么更换品牌,要么干脆停止避孕。国家数据显示,避孕药恐慌与意外怀孕数量大幅增加之间存在密切关联,这在年轻女性中尤为显著,1995 - 1996年至1996 - 1997年间,16岁以下女性使用口服避孕药的比例从40%降至27%。国民医疗服务体系因生育和堕胎增加而产生的成本估计,产科护理约为2100万英镑,堕胎服务约为4600万英镑。为了公众健康,未来应更仔细地评估风险水平,并更谨慎地提供建议。