Iijima H, Iida T, Imai M, Gohdo T, Tsukahara S
Department of Ophthalmology, Yamanashi Medical University, Tamaho, Japan.
Am J Ophthalmol. 2000 Jan;129(1):21-6. doi: 10.1016/s0002-9394(99)00253-6.
To study the cross-section images of orange-red lesions in eyes with idiopathic polypoidal choroidal vasculopathy and compare their protrusions quantitatively with those of serous retinal pigment epithelium detachment.
Optical coherent tomography images scanning remarkable orange-red lesions in eyes with idiopathic polypoidal choroidal vasculopathy and serous retinal pigment epithelium detachment in age-related macular degeneration or central serous chorioretinopathy were prospectively recorded. The correlation between the base diameter and the height of the lesions was analyzed.
Optical coherence tomography images show prominent anterior protrusion of the orange-red lesions. The ratio of the height to the base diameter of the orange-red lesions in eyes with idiopathic polypoidal choroidal vasculopathy is 0.32+/-0.05, and it is significantly larger than lesions in eyes with serous retinal pigment epithelium detachment (0.18+/-0.05, P< .001).
The orange-red lesions in eyes with idiopathic polypoidal choroidal vasculopathy have a more sharply peaked shape than serous retinal pigment epithelium detachment as a subretinal structure, suggesting polypoidal vascular lesions in eyes with idiopathic polypoidal choroidal vasculopathy are situated beneath the Bruch membrane and covered anteriorly with both the retinal pigment epithelium and the Bruch membrane.
研究特发性息肉状脉络膜血管病变眼中橙红色病变的横断面图像，并将其突出程度与浆液性视网膜色素上皮脱离的突出程度进行定量比较。
前瞻性记录年龄相关性黄斑变性或中心性浆液性脉络膜视网膜病变中特发性息肉状脉络膜血管病变眼和浆液性视网膜色素上皮脱离眼中显著橙红色病变的光学相干断层扫描图像。分析病变基底直径与高度之间的相关性。
光学相干断层扫描图像显示橙红色病变有明显的前部突出。特发性息肉状脉络膜血管病变眼中橙红色病变的高度与基底直径之比为0.32±0.05，明显大于浆液性视网膜色素上皮脱离眼中的病变（0.18±0.05，P<0.001）。
特发性息肉状脉络膜血管病变眼中的橙红色病变作为一种视网膜下结构，其形状比浆液性视网膜色素上皮脱离的形状峰值更尖锐，提示特发性息肉状脉络膜血管病变眼中的息肉状血管病变位于布鲁赫膜下方，前部被视网膜色素上皮和布鲁赫膜覆盖。
