与副肿瘤性扁平苔藓相关的瘢痕性结膜炎。
Cicatrizing conjunctivitis associated with paraneoplastic lichen planus.
作者信息
Hahn J M, Meisler D M, Lowder C Y, Tung R C, Camisa C
机构信息
Division of Ophthalmology, The Cleveland Clinic Foundation, Ohio 44195, USA.
出版信息
Am J Ophthalmol. 2000 Jan;129(1):98-9. doi: 10.1016/s0002-9394(99)00291-3.
PURPOSE
To report two cases of cicatrizing conjunctivitis associated with paraneoplastic lichen planus.
METHODS
Case reports.
RESULTS
Two patients were examined because of redness and discomfort in both eyes. A 63-year-old woman with follicular, small-cleaved cell lymphoma had cicatrizing conjunctivitis, stomatitis, vulvitis, and skin lesions. A 25-year-old man with malignant thymoma had cicatrizing conjunctivitis, erosive stomatitis, and penile papules. Histopathologic studies of conjunctiva and skin biopsy specimens in the first patient and labial biopsy specimens in the second revealed lichen planus.
CONCLUSION
Paraneoplastic lichen planus is a possible cause of cicatrizing conjunctivitis associated with inflammatory skin and mucous membrane disease.
目的
报告两例与副肿瘤性扁平苔藓相关的瘢痕性结膜炎病例。
方法
病例报告。
结果
两名患者因双眼发红和不适接受检查。一名63岁患有滤泡性小裂细胞淋巴瘤的女性有瘢痕性结膜炎、口腔炎、外阴炎和皮肤病变。一名25岁患有恶性胸腺瘤的男性有瘢痕性结膜炎、糜烂性口腔炎和阴茎丘疹。对首例患者的结膜和皮肤活检标本以及第二例患者的唇部活检标本进行组织病理学研究，均显示为扁平苔藓。
结论
副肿瘤性扁平苔藓可能是与炎症性皮肤和黏膜疾病相关的瘢痕性结膜炎的病因。
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