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表现为瘢痕性结膜炎的支气管源性鳞状细胞癌。

Bronchogenic squamous cell carcinoma presenting as cicatrizing conjunctivitis.

作者信息

Vroman David T, Breckenridge Rebecca Reid, Solomon Kerry D, Sandoval Helga P, Fernández de Castro Luis E

机构信息

Magill Research Center for Vision Correction, Storm Eye Institute, Medical University of South Carolina, Charleston, SC 29425, USA.

出版信息

Cornea. 2006 Jun;25(5):611-3. doi: 10.1097/01.ico.0000196447.79817.ce.

Abstract

PURPOSE

To report a case of cicatrizing conjunctivitis as the initial manifestation of a bronchogenic squamous cell carcinoma.

METHODS

Case report of a 57-year-old patient with bilateral history of ocular pain, redness, and discharge, with no apparent predisposing factors. Examination revealed chemosis, pseudomembrane, and symblepharon formation, and multiple ulcerated pustular and vesicular periocular and perioral lesions literature review.

RESULTS

Skin biopsy was compatible with bullous pemphigoid. Two months later he developed respiratory symptoms, and a squamous cell carcinoma was diagnosed.

CONCLUSIONS

This case demonstrates cicatrizing conjunctivitis as a possible paraneoplastic syndrome associated with squamous cell lung carcinoma.

摘要

目的

报告一例瘢痕性结膜炎作为支气管源性鳞状细胞癌初始表现的病例。

方法

病例报告,一名57岁患者有双侧眼痛、眼红和分泌物史,无明显诱发因素。检查发现结膜水肿、假膜和睑球粘连形成,以及眼周和口周有多个溃疡性脓疱和水疱性病变(文献综述)。

结果

皮肤活检符合大疱性类天疱疮。两个月后他出现呼吸道症状,诊断为鳞状细胞癌。

结论

本病例表明瘢痕性结膜炎可能是与肺鳞状细胞癌相关的副肿瘤综合征。

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