Cursiefen C, Wisse M, Cursiefen S, Jünemann A, Martus P, Korth M
Department of Ophthalmology and the Institute of Medical Informatics, Biometry and Epidemiology, University of Erlangen-Nürnberg, Erlangen, Germany.
Am J Ophthalmol. 2000 Jan;129(1):102-4. doi: 10.1016/s0002-9394(99)00289-5.
To analyze the association of normal-pressure glaucoma and migraine.
In a prospective study, 154 patients with glaucoma (56 normal-pressure subgroup and 98 high-pressure glaucoma subgroup), 55 patients with ocular hypertension, and 75 control subjects were analyzed by means of a standardized questionnaire based on International Headache Society criteria.
According to the questionnaire, 46 patients (17%) were classified as suffering from migraine and 20 (7%) from tension headache (episodic and chronic). The prevalence of headache, migraine, and tension headache did not vary significantly among control subjects, patients with ocular hypertension, and patients with glaucoma, but migraine was significantly more common in patients with normal-pressure glaucoma (28%) compared with control subjects (12%; P<.05) and patients with high-pressure glaucoma (10%; P<.01).
The results suggest an association of normal-pressure glaucoma and migraine and a potential, common vascular etiology of both diseases.
分析正常眼压性青光眼与偏头痛之间的关联。
在一项前瞻性研究中,通过基于国际头痛协会标准的标准化问卷对154例青光眼患者(56例正常眼压亚组和98例高眼压青光眼亚组)、55例高眼压症患者以及75例对照受试者进行分析。
根据问卷,46例患者(17%)被归类为患有偏头痛,20例(7%)患有紧张性头痛(发作性和慢性)。对照受试者、高眼压症患者和青光眼患者中头痛、偏头痛和紧张性头痛的患病率无显著差异,但正常眼压性青光眼患者中偏头痛的发生率(28%)显著高于对照受试者(12%;P<0.05)和高眼压青光眼患者(10%;P<0.01)。
结果提示正常眼压性青光眼与偏头痛之间存在关联,且两种疾病可能存在共同的血管病因。