McPherson R
Ottawa Heart Institute, Ottawa, Canada.
Can J Cardiol. 2000 Jan;16 Suppl A:5A-10A.
Coronary artery disease (CAD) is the leading cause of death for women. In large part because of increased age at presentation and a greater frequency of concomitant morbidities, women who develop CAD have a poorer prognosis than do men. Although the long term outcome of revascularization procedures is good, the associated procedural morbidity and mortality in women is high. More emphasis should be placed on the primary and secondary prevention of CAD in women. Although women respond well to risk factor modification, including lipid-lowering therapies, recent data indicate that their awareness of risk factors and prevention strategies is poor. Physician risk factor assessment and adherence to current guideline recommendations are essential in preventing the development or progression of CAD in women.
冠状动脉疾病(CAD)是女性死亡的主要原因。很大程度上由于发病年龄增加以及合并症出现频率更高,患CAD的女性比男性预后更差。尽管血运重建手术的长期效果良好,但女性相关的手术并发症和死亡率很高。应更加重视女性CAD的一级和二级预防。尽管女性对包括降脂治疗在内的危险因素改变反应良好,但最近的数据表明她们对危险因素和预防策略的认识较差。医生对危险因素的评估以及遵循当前指南建议对于预防女性CAD的发生或进展至关重要。