土壤杆菌素，一种来自海洋土壤杆菌的新型细胞毒性抗生素。分类学、发酵、分离、理化性质及生物活性
Agrochelin, a new cytotoxic antibiotic from a marine Agrobacterium. Taxonomy, fermentation, isolation, physico-chemical properties and biological activity.
作者信息
Acebal C, Cañedo L M, Puentes J L, Baz J P, Romero F, de la Calle F, Grávalos M D, Rodriguez P
机构信息
Instituto Biomar S.A. Pol. Ind. de Leon. Edif. CEI, Onzonilla, León, Spain.
出版信息
J Antibiot (Tokyo). 1999 Nov;52(11):983-7. doi: 10.7164/antibiotics.52.983.
PMID:10656570
Abstract
Agrochelin, a new alkaloid cytotoxic substance, was produced by the fermentation of Agrobacterium sp. The compound was obtained from the bacterial cells by solvent extraction and purified by silica gel chromatography. Agrochelin (1) and its acetyl derivative (2) exhibited cytotoxic activity.
摘要
农杆菌素是一种新的生物碱细胞毒性物质，由土壤杆菌属发酵产生。该化合物通过溶剂萃取从细菌细胞中获得，并通过硅胶柱色谱法纯化。农杆菌素（1）及其乙酰衍生物（2）具有细胞毒性活性。
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