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来自捕食线虫真菌弗氏节丛孢菌的环己烯氧化物抗生素弗拉格拉诺酮A、B和C的结构

Structures of flagranones A, B and C, cyclohexenoxide antibiotics from the nematode-trapping fungus Duddingtonia flagrans.

作者信息

Anderson M G, Rickards R W, Lacey E

机构信息

Research School of Chemistry, Australian National University, Canberra, ACT.

出版信息

J Antibiot (Tokyo). 1999 Nov;52(11):1023-8. doi: 10.7164/antibiotics.52.1023.

DOI:10.7164/antibiotics.52.1023
PMID:10656575
Abstract

Spectroscopic data define the structures of the flagranones A (2), B (3) and C (4) from the nematode-trapping fungus Duddingtonia flagrans. These antibiotics are structurally related to the farnesylated cyclohexenoxides of the oligosporon group recently isolated from the nematode-trapping fungus Arthrobotrys oligospora, and show similar antimicrobial activity.

摘要

光谱数据确定了捕食线虫真菌达丁顿丝孢菌中弗拉格拉诺酮A（2）、B（3）和C（4）的结构。这些抗生素在结构上与最近从捕食线虫真菌少孢节丛孢中分离出的寡孢菌素组的法尼基化环己烯氧化物相关，并表现出相似的抗菌活性。

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