Anderson M G, Jarman T B, Rickards R W
Research School of Chemistry, Australian National University, Canberra.
J Antibiot (Tokyo). 1995 May;48(5):391-8. doi: 10.7164/antibiotics.48.391.
Spectroscopic data define the structures of three new antibiotics, 4',5'-dihydro-oligosporon (4), hydroxyoligosporon (5) and 10',11'-epoxyoligosporon (6) from the nematode-trapping fungus Arthrobotrys oligospora, and confirm the structures of the recently reported antibiotics oligosporon (1) and oligosporol B (3). The absolute configuration of the substituted 7-oxabicyclo[4.1.0]hept-3-ene nucleus of these metabolites is determined by circular dichroic spectroscopy. Oligosporon (1) and its dihydro-derivative (4) represent the second and most complex structural type of nematocidal metabolite to be characterised from cultures of nematophagous fungi.
光谱数据确定了来自捕食线虫真菌少孢节丛孢（Arthrobotrys oligospora）的三种新抗生素4',5'-二氢寡孢菌素（4）、羟基寡孢菌素（5）和10',11'-环氧寡孢菌素（6）的结构，并证实了最近报道的抗生素寡孢菌素（1）和寡孢醇B（3）的结构。这些代谢产物中取代的7-氧杂双环[4.1.0]庚-3-烯核的绝对构型通过圆二色光谱法确定。寡孢菌素（1）及其二氢衍生物（4）代表了从食线虫真菌培养物中鉴定出的第二种也是最复杂的杀线虫代谢物结构类型。
