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[利用间接血凝反应检测急性化脓性破坏性肺炎患者血清中绿脓杆菌抗体]

[Use of the indirect hemagglutination reaction for detecting antibodies to Pseudomonas pyocyanea in acute suppurative destructive pneumonia].

作者信息

Oleĭnik I I, Rodionova S N, Bychkov V A, Sakharova A E

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1978 Sep(9):70-4.

PMID:106610
Abstract

No less than 4-fold increase in the antibody titres to Pseudomonas aeruginosa during the infectious process served as laboratory confirmation of its participation in the infectious process. In 49 of 91 patients hemagglutining titre exceeded the diagnostic one (1:640). In 9 patients (chiefly in infants) hemagglutinin titre remained low, but there was a rise of antibody level to Pseudomonas aeruginosa during the disease. High hemagglutinin titres were noted in 12 patients on admission to the clinic, with reduction of the antibody titres at the late periods of the disease. Antibody titres remained unchanged during the disease in 15 patients. In 3 cases the indirect hemagglutination test was assesed as negative. In the rest of the patients hemagglutinin titres varied within the range of the diagnostic titre. Thus, the indirect hemagglutination test with erythrocytic diagnostic agent permitting to determine antibodies to Pseudomonas aeruginosa could be used at the clinic in combination with bacteriological and other investigations for establishing etiology of the destructive process.

摘要

在感染过程中,抗铜绿假单胞菌抗体滴度至少增加4倍,作为其参与感染过程的实验室确认依据。91例患者中有49例血凝滴度超过诊断值(1:640)。9例患者(主要是婴儿)血凝素滴度仍较低,但在疾病过程中抗铜绿假单胞菌抗体水平有所升高。12例患者入院时血凝素滴度较高,在疾病后期抗体滴度降低。15例患者在疾病过程中抗体滴度保持不变。3例间接血凝试验结果为阴性。其余患者的血凝素滴度在诊断滴度范围内波动。因此,使用红细胞诊断剂的间接血凝试验可用于检测抗铜绿假单胞菌抗体,在临床上可与细菌学及其他检查相结合,以确定破坏性病变的病因。

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