Petrás G, Adám M, Lányi B, Konkoly Thege M, Szentmihályi A
Acta Microbiol Hung. 1984;31(2):109-16.
In 39 patients of a respiratory intensive care unit the intensity of the serological response to the purified LPS of the causative Pseudomonas aeruginosa was found to change according to the site of infection. The highest titres were found in septic cases, when the antigenic assault reached all the immune-competent cells in the body. Short presence (only one positive bacteriological culture) of P. aeruginosa at the site of inflammation resulted in a low or moderate rise in antibody titre. Ten days were enough for the development of a maximum total antibody (approximately IgM) response, while IgG type antibodies moderately grew further when the presence of P. aeruginosa lasted more than 10 days. Only a 16-fold increase in total antibodies per se or a 4-fold rise in both total (approximately IgM) and IgG antibodies confirmed the pseudomonas infection.
在一家呼吸重症监护病房的39名患者中，发现针对致病性铜绿假单胞菌纯化脂多糖的血清学反应强度会根据感染部位而变化。在脓毒症病例中，当抗原攻击波及体内所有免疫活性细胞时，抗体滴度最高。炎症部位铜绿假单胞菌短暂存在（仅一次阳性细菌培养）会导致抗体滴度低或中度升高。十天足以产生最大的总抗体（约为IgM）反应，而当铜绿假单胞菌存在超过10天时，IgG型抗体则会适度进一步增长。仅总抗体本身增加16倍或总抗体（约为IgM）和IgG抗体均增加4倍才能确诊铜绿假单胞菌感染。
