Borisy G G, Svitkina T M
Laboratory of Molecular Biology, University of Wisconsin, Madison, WI 53706, USA.
Curr Opin Cell Biol. 2000 Feb;12(1):104-12. doi: 10.1016/s0955-0674(99)00063-0.
The reconstitution of microbial rocketing motility in vitro with purified proteins has recently established definitively that no myosin motor is required for protrusion. Instead, actin polymerization, in conjunction with a small number of proteins, is sufficient. A dendritic pattern of nucleation controlled by the Arp2/3 complex provides an efficient pushing force for lamellipodial motility.
最近通过纯化蛋白在体外重建微生物的火箭式运动，最终确定了细胞突起不需要肌球蛋白马达。相反，肌动蛋白聚合作用与少量蛋白质共同作用就足够了。由Arp2/3复合体控制形成的树枝状成核模式为片状伪足运动提供了有效的推动力。
