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在精英女子手球运动员中,脱氢表雄酮(DHEA)而非睾酮显示出运动后唾液雄激素反应。

Dehydroepiandrosterone (DHEA) rather than testosterone shows saliva androgen responses to exercise in elite female handball players.

作者信息

Filaire E, Lac G

机构信息

Laboratoire de la Performance Motrice, U.F.R. S.T.A.P.S., Université Blaise Pascal, Clermont-Ferrand II, Aubière, France.

出版信息

Int J Sports Med. 2000 Jan;21(1):17-20. doi: 10.1055/s-2000-8851.

DOI:10.1055/s-2000-8851
PMID:10683093
Abstract

The aim of the investigation was to evaluate in fourteen elite female handball players the resting values of saliva levels of testosterone -- T -- and dehydroepiandrosterone -- DHEA -- in comparison with ten sedentary women and the response to exercise of the same hormones in handball players. Saliva samples were taken from the handball players upon wakening (resting values) (8 a. m.), 5 minutes before and after a simulated handball match (6 p. m.; 8 p. m.) and upon wakening the following morning (8 a. m. + 24 h). The samples of saliva from the sedentary controls were taken at the same time of day but the controls did not perform any exercise. Resting hormonal levels were lower in handball players than in controls (P < 0.01). The exercise did not induce significant changes in T and DHEA salivary concentrations in handball players. Positive correlations between testosterone concentrations and DHEA were observed at all the time points studied. These findings showed that the T and DHEA concentrations followed a remarkably similar pattern. Considering the very low concentrations of testosterone in women, in particular in saliva, and its biosynthetic pathway, we suggest that measurements of DHEA could serve as a substitute for testosterone measurements to study training responses in elite sportswomen.

摘要

该研究的目的是评估14名精英女子手球运动员的唾液睾酮(T)和脱氢表雄酮(DHEA)的静息值,并与10名久坐不动的女性进行比较,同时研究手球运动员中这些激素对运动的反应。在手球运动员醒来时(静息值)(上午8点)、模拟手球比赛前5分钟和比赛后(下午6点;晚上8点)以及第二天早上醒来时(上午8点 + 24小时)采集唾液样本。久坐对照组的唾液样本在一天中的相同时间采集,但对照组不进行任何运动。手球运动员的静息激素水平低于对照组(P < 0.01)。运动并未在手球运动员中引起T和DHEA唾液浓度的显著变化。在所有研究的时间点都观察到睾酮浓度与DHEA之间存在正相关。这些发现表明,T和DHEA浓度遵循非常相似的模式。考虑到女性尤其是唾液中睾酮的浓度非常低及其生物合成途径,我们建议测量DHEA可以替代睾酮测量,以研究精英女运动员的训练反应。

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