Groenewoud J H, van der Heide A, Onwuteaka-Philipsen B D, Willems D L, van der Maas P J, van der Wal G
Department of Public Health, Erasmus University, Rotterdam, The Netherlands.
N Engl J Med. 2000 Feb 24;342(8):551-6. doi: 10.1056/NEJM200002243420805.
The characteristics and frequency of clinical problems with the performance of euthanasia and physician-assisted suicide are uncertain. We analyzed data from two studies of euthanasia and physician-assisted suicide in The Netherlands (one conducted in 1990 and 1991 and the other in 1995 and 1996), with a total of 649 cases. We categorized clinical problems as technical problems, such as difficulty inserting an intravenous line; complications, such as myoclonus or vomiting; or problems with completion, such as a longer-than-expected interval between the administration of medications and death.
In 114 cases, the physician's intention was to provide assistance with suicide, and in 535, the intention was to perform euthanasia. Problems of any type were more frequent in cases of assisted suicide than in cases of euthanasia. Complications occurred in 7 percent of cases of assisted suicide, and problems with completion (a longer-than-expected time to death, failure to induce coma, or induction of coma followed by awakening of the patient) occurred in 16 percent of the cases; complications and problems with completion occurred in 3 percent and 6 percent of cases of euthanasia, respectively. The physician decided to administer a lethal medication in 21 of the cases of assisted suicide (18 percent), which thus became cases of euthanasia. The reasons for this decision included problems with completion (in 12 cases) and the inability of the patient to take all the medications (in 5).
There may be clinical problems with the performance of euthanasia and physician-assisted suicide. In The Netherlands, physicians who intend to provide assistance with suicide sometimes end up administering a lethal medication themselves because of the patient's inability to take the medication or because of problems with the completion of physician-assisted suicide.
安乐死及医生协助自杀实施过程中临床问题的特征及发生频率尚不明确。我们分析了荷兰两项关于安乐死及医生协助自杀的研究数据(一项于1990年和1991年开展,另一项于1995年和1996年开展),共计649例。我们将临床问题分为技术问题,如静脉穿刺困难;并发症,如肌阵挛或呕吐;或完成过程中的问题,如用药至死亡的间隔时间长于预期。
在114例中,医生的意图是协助自杀,535例中意图是实施安乐死。协助自杀案例中任何类型的问题都比安乐死案例中更频繁。协助自杀案例中有7%发生并发症,16%出现完成过程中的问题(死亡时间长于预期、未能诱导昏迷或诱导昏迷后患者苏醒);安乐死案例中并发症和完成过程中的问题分别发生在3%和6%的案例中。在21例协助自杀案例(18%)中,医生决定给予致命药物,从而使其成为安乐死案例。做出这一决定的原因包括完成过程中的问题(12例)和患者无法服用所有药物(5例)。
安乐死及医生协助自杀的实施可能存在临床问题。在荷兰,意图协助自杀的医生有时会因患者无法服药或医生协助自杀完成过程中出现问题而最终自行给予致命药物。