Acacio B D, Gottfried T, Israel R, Sokol R Z
Los Angeles County/University of Southern California School of Medicine, Women's and Children's Hospital, Los Angeles, California, USA.
Fertil Steril. 2000 Mar;73(3):595-7. doi: 10.1016/s0015-0282(99)00591-9.
To determine: [1] what percentage of men in an infertile relationship will have a semen abnormality, [2] the average value for each semen parameter in this group of men, [3] the distribution of abnormal semen parameters in this group, and [4] if our data support the hypothesis that sperm concentration is declining.
Retrospective cohort study.
County hospital university-based infertility clinic.
PATIENT(S): Male partners of women presenting for an infertility evaluation.
INTERVENTION(S): Semen specimens were collected after 2-5 days of abstinence.
MAIN OUTCOME MEASURE(S): Sperm concentration, motility, and morphology.
RESULT(S): Fifty-two percent of samples had at least one sperm abnormality based on World Health Organization criteria. Fifty-one percent had an abnormality in sperm motility, 18% in sperm concentration, and 14% in sperm morphology. Four percent of the patients were azoospermic.
CONCLUSION(S): No decline in sperm density was revealed in semen collected by men presenting for an initial screening semen analysis.
确定：[1] 处于不育关系中的男性精液异常的比例；[2] 该组男性各项精液参数的平均值；[3] 该组精液参数异常的分布情况；以及 [4] 我们的数据是否支持精子浓度正在下降这一假设。
回顾性队列研究。
以大学为基础的县医院不孕不育诊所。
前来进行不孕不育评估的女性的男性伴侣。
禁欲2 - 5天后采集精液样本。
精子浓度、活力和形态。
根据世界卫生组织标准，52%的样本至少有一项精子异常。51%的样本精子活力异常，18%精子浓度异常，14%精子形态异常。4%的患者无精子症。
初次进行精液分析筛查的男性所采集精液中未发现精子密度下降。
