McGivern B, Pemberton M, Theaker E D, Buchanan J A, Thornhill M H
University Dental Hospital of Manchester.
Br Dent J. 2000 Jan 22;188(2):73-6. doi: 10.1038/sj.bdj.4800392.
Hypersensitivity to the constituents of dental amalgam is uncommon. When it occurs it typically manifests itself as a lichenoid reaction involving a delayed, type IV, cell-mediated hypersensitivity response. Rarely, a more acute and generalised response can occur involving both the oral mucosa and skin. We describe two cases that illustrate the presentation and management of these two types of reaction.