Lauque S, Arnaud-Battandier F, Mansourian R, Guigoz Y, Paintin M, Nourhashemi F, Vellas B
CHU Purpan-Casselardit, Service du professeur Albaréde, Toulouse, France.
Age Ageing. 2000 Jan;29(1):51-6. doi: 10.1093/ageing/29.1.51.
To validate a nutritional intervention programme for elderly people living in nursing homes.
In a prospective, randomized, controlled study of 88 residents, we determined nutritional status at day 0 and day 60 using a record of dietary intake, anthropometry, hand-grip strength and mini-nutritional assessment. Dietary intake, grip strength and body weight were also recorded at day 30. We divided subjects into four groups according to their mini-nutritional assessment score. Those with a score 24 received no oral supplementation. Those at risk of malnutrition (with a score of 17-23.5) were randomized to oral supplementation. Those with a score <17 received oral supplementation. We recorded the amount of oral supplements consumed daily.
Compliance with oral supplementation was good, and daily intake averaged about 400 kcal. The total energy intake on day 60 was significantly higher in both of the groups that received supplements. Following supplementation, most subjects at risk of malnutrition improved their mini-nutritional assessment score and increased their weight (by 1.4 +/- 0.5 kg). Neither the mini-nutritional assessment score nor weight improved in subjects at risk of malnutrition who did not receive supplements. Supplementation in the malnourished group resulted in a mean mini-nutritional assessment score increase (from 13.9 +/- 2.6 to 17.1 +/- 3.9) and a mean weight gain of 1.5 +/- 0.4 kg.
Oral nutritional supplements are well accepted and result in increased daily protein and energy intake, body weight and nutritional status in most malnourished patients and in those at risk of malnutrition.
验证一项针对养老院老年人的营养干预计划。
在一项对88名居民进行的前瞻性、随机对照研究中，我们在第0天和第60天使用饮食摄入记录、人体测量、握力和微型营养评定来确定营养状况。在第30天也记录了饮食摄入、握力和体重。我们根据微型营养评定分数将受试者分为四组。分数≥24的受试者不接受口服补充剂。有营养不良风险（分数为17 - 23.5）的受试者被随机分配接受口服补充剂。分数<17的受试者接受口服补充剂。我们记录了每日口服补充剂的摄入量。
口服补充剂的依从性良好，每日摄入量平均约为400千卡。接受补充剂的两组在第60天的总能量摄入量均显著更高。补充后，大多数有营养不良风险的受试者提高了他们的微型营养评定分数并增加了体重（增加了1.4±0.5千克）。未接受补充剂的有营养不良风险的受试者，其微型营养评定分数和体重均未改善。营养不良组补充后微型营养评定分数平均增加（从13.9±2.6增至17.1±3.9），平均体重增加1.5±0.4千克。
口服营养补充剂被广泛接受，并能增加大多数营养不良患者和有营养不良风险患者的每日蛋白质和能量摄入量、体重及营养状况。
