Arevalo J F, Shields C L, Shields J A, Hykin P G, De Potter P
Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Ophthalmology. 2000 Feb;107(2):344-50. doi: 10.1016/s0161-6420(99)00051-2.
To determine the characteristic features of indocyanine green videoangiography (ICG-V) of circumscribed choroidal hemangioma.
Prospective, observational case series.
Twenty-five eyes of 25 consecutive patients with circumscribed choroidal hemangioma.
Indocyanine green videoangiography and intravenous fluorescein angiography (IVFA) were prospectively performed and reviewed. The specific features on ICG-V were compared with features of IVFA.
The behavior of circumscribed choroidal hemangioma cases was observed with ICG-V and IVFA.
On ICG-V, earliest hyperfluorescence of circumscribed choroidal hemangioma was achieved at a mean of 27.6 seconds (range, 13-62 seconds), whereas maximum hyperfluorescence occurred at 222 seconds (range, 33-707 seconds). In the late frames, all eyes demonstrated a relative decrease in fluorescence, including 18 eyes (72%) that demonstrated "washout" of the dye. Other findings on ICG-V included intrinsic vessels in 19 eyes (76%), a late hyperfluorescent rim in 19 eyes (76%), and late frame hot spots in 14 eyes (56%). On IVFA, the earliest hyperfluorescence was achieved at a mean of 24 seconds (range, 10-66 seconds), whereas maximum hyperfluorescence occurred at a mean of 76.3 seconds (range, 21-720 seconds). Increasing hyperfluorescence in the late frames was found in all cases. Other findings included intrinsic vessels in 12 eyes (48%) and hot spots in the late frames in 9 eyes (36%).
Circumscribed choroidal hemangioma have specific characteristics on ICG-V that are not visualized with IVFA. We believe that ICG-V may become an important noninvasive tool for the diagnosis of choroidal hemangioma.
确定局限性脉络膜血管瘤的吲哚菁绿视频血管造影(ICG-V)特征。
前瞻性观察病例系列。
25例连续性局限性脉络膜血管瘤患者的25只眼。
前瞻性地进行吲哚菁绿视频血管造影和静脉荧光素血管造影(IVFA)并进行回顾。将ICG-V的特定特征与IVFA的特征进行比较。
用ICG-V和IVFA观察局限性脉络膜血管瘤病例的表现。
在ICG-V上,局限性脉络膜血管瘤最早出现高荧光的平均时间为27.6秒(范围13 - 62秒),而最大高荧光出现在222秒(范围33 - 707秒)。在晚期图像中,所有眼均显示荧光相对减弱,其中18只眼(72%)显示染料“消退”。ICG-V的其他表现包括19只眼(76%)有内部血管,19只眼(76%)有晚期高荧光边缘,14只眼(56%)有晚期图像热点。在IVFA上,最早出现高荧光的平均时间为24秒(范围10 - 66秒),而最大高荧光平均出现在76.3秒(范围21 - 720秒)。所有病例在晚期图像中均发现荧光增强。其他表现包括12只眼(48%)有内部血管,9只眼(36%)有晚期图像热点。
局限性脉络膜血管瘤在ICG-V上有IVFA无法显示的特定特征。我们认为ICG-V可能成为诊断脉络膜血管瘤的重要无创工具。