Okada K, Hayashi T, Tsumura K, Suematsu C, Endo G, Fujii S
Medical Center for Employees' Health, Osaka Gas Co. Ltd, Japan.
Diabet Med. 2000 Jan;17(1):53-8. doi: 10.1046/j.1464-5491.2000.00229.x.
To investigate association between leisure-time physical activity at weekends and the risk of developing Type 2 diabetes mellitus (DM).
Prospective examination of 6,013 Japanese men aged 35-60 years who were free of DM, impaired fasting glycaemia, or hypertension at study entry. Type 2 DM was defined by a fasting plasma glucose level > or = 7.0 mmol/l or a 2-h post-load plasma glucose level > or =11.1 mmol/l. Data on physical activity obtained from questionnaires consisted of overall leisure-time physical activity weekly and leisure-time physical activity at weekends.
During the 59,966 person-years follow-up, 444 cases developed Type 2 DM. Regular physical exercise at least once a week was associated with a reduced risk of Type 2 DM. After adjustments for age, body mass index, daily alcohol consumption, smoking habits, blood pressure levels and a parental history of Type 2 DM, men who engaged in regular physical exercise at least once a week had a relative risk of Type 2 DM of 0.75 (95% CI, 0.61-0.93) compared with men engaging in exercise less often. Even vigorous activity only once a week at weekends was associated with a reduced risk of Type 2 DM. Men who engaged in vigorous activity at least once a week at weekends had a multiple-adjusted relative risk of Type 2 DM of 0.55 (95% CI, 0.35-0.88) compared with sedentary men.
Regular physical exercise at least once a week and vigorous activity even only once a week at weekends are associated with a decreased risk of Type 2 DM.
研究周末休闲时间的体育活动与2型糖尿病（DM）发病风险之间的关联。
对6013名年龄在35至60岁之间、研究开始时无糖尿病、空腹血糖受损或高血压的日本男性进行前瞻性检查。2型糖尿病的定义为空腹血糖水平≥7.0 mmol/l或负荷后2小时血糖水平≥11.1 mmol/l。通过问卷调查获得的体育活动数据包括每周总的休闲时间体育活动和周末休闲时间体育活动。
在59966人年的随访期间，444例发生了2型糖尿病。每周至少进行一次规律体育锻炼与2型糖尿病风险降低相关。在对年龄、体重指数、每日饮酒量、吸烟习惯、血压水平和2型糖尿病家族史进行调整后，与锻炼较少的男性相比，每周至少进行一次规律体育锻炼的男性患2型糖尿病的相对风险为0.75（95%可信区间，0.61 - 0.93）。即使仅在周末每周进行一次剧烈活动也与2型糖尿病风险降低相关。与久坐不动的男性相比，在周末每周至少进行一次剧烈活动的男性经多因素调整后患2型糖尿病的相对风险为0.55（95%可信区间，0.35 - 0.88）。
每周至少进行一次规律体育锻炼以及即使仅在周末每周进行一次剧烈活动均与2型糖尿病风险降低相关。
