Okawa Takafumi, Negishi Hikaru, Aoki Yuki, Uchida Mitsuo, Sato Yumi, Ishikawa Mai, Matsui Rie, Hotta Kaori, Saitoh Takayuki
Department of Mathematics and Data science, Graduate School of Medicine, Gunma University, Gunma, Japan.
Department of Laboratory Sciences, Graduate school of Health Sciences, Gunma University, Gunma, Japan.
PLoS One. 2025 Jul 29;20(7):e0327505. doi: 10.1371/journal.pone.0327505. eCollection 2025.
Questionnaires are used to collect data on lifestyle behaviors during specific health checkups; however, the results cannot conclusively determine whether the behaviors influence the onset of lifestyle diseases. By analyzing data from a retrospective cohort, this study aimed to determine the specific lifestyle behaviors that most strongly contribute to the onset of lifestyle diseases, such as metabolic syndrome, hypertension, diabetes, and dyslipidemia.
We administrated the data of 924,932 individuals insured under Gunma Prefecture's National Health Insurance who underwent specific health checkups between 2011 and 2016. A logistic regression analysis was conducted to assess the association between the responses to 10 lifestyle questions and the future onset of lifestyle diseases.
We examined 47,803 individuals who were not identified with lifestyle disorders at the initial checkup. In this study, weight gain of ≥10 kg since the age of 20 years showed the strongest association with MetS (OR: 2.01; 95% CI, 1.79-2.25). Additionally, smoking and weight gain were identified as common risk factors for MetS, hypertension, and dyslipidemia. The results revealed that lifestyle behaviors are longitudinally associated with the onset of lifestyle diseases.
The use of self-administered questionnaires to assess lifestyle behaviors can effectively predict future health risks.
问卷调查用于在特定健康检查期间收集生活方式行为的数据;然而,结果无法确凿地确定这些行为是否会影响生活方式疾病的发病。通过分析回顾性队列的数据,本研究旨在确定对代谢综合征、高血压、糖尿病和血脂异常等生活方式疾病的发病贡献最大的具体生活方式行为。
我们管理了2011年至2016年间在群马县国民健康保险下接受特定健康检查的924,932名参保人员的数据。进行了逻辑回归分析,以评估对10个生活方式问题的回答与未来生活方式疾病发病之间的关联。
我们检查了47,803名在初次检查时未被诊断为生活方式紊乱的个体。在本研究中,20岁以后体重增加≥10kg与代谢综合征的关联最为强烈(OR:2.01;95%CI,1.79-2.25)。此外,吸烟和体重增加被确定为代谢综合征、高血压和血脂异常的常见危险因素。结果表明,生活方式行为与生活方式疾病的发病存在纵向关联。
使用自填式问卷评估生活方式行为可以有效地预测未来的健康风险。