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使用二氧化碳/铒钇铝石榴石联合激光对面部进行激光皮肤重建。

Laser skin resurfacing of the face with a combined CO2/Er:YAG laser.

作者信息

Goldman M P, Marchell N, Fitzpatrick R E

机构信息

Dermatology/Cosmetic Laser Associates of San Diego County, Inc., La Jolla, California 92037, USA.

出版信息

Dermatol Surg. 2000 Feb;26(2):102-4. doi: 10.1046/j.1524-4725.2000.98208.x.

Abstract

BACKGROUND

A combined, dual-wavelength CO2/Er:YAG laser system having the ability to deliver both clean ablation of skin with the erbium wavelength and a simultaneous deeper penetrating subablative thermal pulse of CO2 was developed for full-face resurfacing. The CO2 component can be pulsed from 1 to 100 msec at a power of 1-10 W with the Er:YAG component pulsed at 350 microsec at 1.7 J/cm2 through either a computer pattern generator with 3 mm diameter spot size or through a noncollimated spot ranging from 0.2 to 8 mm in diameter. Our previous study using this laser on the neck using a 4-8 mm diameter spot with Er:YAG fluence at 1.7 J and the CO2 at 5 W with a 50 msec pulse at a frequency of 10 Hz showed a higher degree of overall patient satisfaction, as well as improvement in skin texture and skin color, compared to patients treated with an Er:YAG laser alone.

OBJECTIVE

This study evaluated the CO2/Er:YAG laser treatment modality in facial resurfacing.

METHODS

Ten patients were treated with four passes at 1.7 J with a 4 mm diameter spot and the CO2 at 5 W with a 50-msec pulse at a frequency of 10 Hz. Photoaging scores as well as thermal damage and new collagen formation were compared immediately before and after treatment as well as at 2 weeks and 3 months postoperatively.

RESULTS

The average pretreatment periorbital score was 6.2 The average posttreatment periorbital scores were 4.2 (P =.0239) at 2 weeks postoperatively (32% improvement) and 3.8 (P =.0028) at 3 months postoperatively (38% improvement). The average pretreatment perioral score was 5.9. The average posttreatment perioral scores were 3.0 (P =.0001) at 2 weeks postoperatively (49% improvement) and 3.3 (P =.0009) at 3 months postoperatively (44% improvement). The average pretreatment cheek score was 4.7. The average posttreatment cheek scores were 2.7 (P =.0066) at 2 weeks postoperatively (43% improvement) and 3.8 (P =. 0152) at 3 months postoperatively (36% improvement). The average pretreatment forehead score was 4.7. The average posttreatment forehead scores were 3.8 (P =.0340) at 2 weeks postoperatively (33% improvement) and 3.6 (P =.0147) at 3 months postoperatively (37% improvement). The average depth of collagen measured in the dermis pretreatment was 29 microm. The average depth of collagen 3 months posttreatment was 54 microm. This is an average increase of 25 microm or an 86% increase in collagen (P =.006). The average thermal damage immediately after treatment was 20 microm.

CONCLUSION

The CO2/Er:YAG laser utilized with four passes at the above-mentioned parameters results in a similar degree of improvement as other forms of laser resurfacing with high-energy, short-pulsed CO2 lasers.

摘要

背景

为全面部皮肤磨削术开发了一种组合式双波长二氧化碳/铒:钇铝石榴石激光系统,该系统能够利用铒波长对皮肤进行清洁消融,并同时利用二氧化碳产生更深层穿透的亚消融热脉冲。二氧化碳组件可在1 - 10瓦的功率下以1至100毫秒的脉冲进行发射,铒:钇铝石榴石组件则通过直径为3毫米光斑尺寸的计算机图案发生器或直径为0.2至8毫米的非准直光斑,以1.7焦耳/平方厘米的能量在350微秒内进行脉冲发射。我们之前的研究在颈部使用该激光,采用直径4 - 8毫米的光斑,铒:钇铝石榴石能量密度为1.7焦耳,二氧化碳功率为5瓦,脉冲宽度为50毫秒,频率为10赫兹,结果显示与单独使用铒:钇铝石榴石激光治疗的患者相比,患者总体满意度更高,皮肤质地和肤色也有所改善。

目的

本研究评估二氧化碳/铒:钇铝石榴石激光治疗方式在面部皮肤磨削术中的效果。

方法

10名患者接受治疗,采用直径4毫米的光斑,铒:钇铝石榴石能量密度为1.7焦耳,进行4次照射,同时二氧化碳功率为5瓦,脉冲宽度为50毫秒,频率为10赫兹。在治疗前、治疗后即刻、术后2周和3个月时比较光老化评分以及热损伤和新胶原蛋白形成情况。

结果

术前眶周平均评分为6.2。术后2周眶周平均评分为4.2(P = 0.0239)(改善32%),术后3个月为3.8(P = 0.0028)(改善38%)。术前口周平均评分为5.9。术后2周口周平均评分为3.0(P = 0.0001)(改善49%),术后3个月为3.3(P = 0.0009)(改善44%)。术前面颊平均评分为4.7。术后2周面颊平均评分为2.7(P = 0.0066)(改善43%),术后3个月为3.8(P = 0.0152)(改善36%)。术前额头平均评分为4.7。术后2周额头平均评分为3.8(P = 0.0340)(改善33%),术后3个月为3.6(P = 0.0147)(改善37%)。术前真皮层测量的胶原蛋白平均深度为29微米。术后3个月胶原蛋白平均深度为54微米。这意味着胶原蛋白平均增加了25微米,即增加了86%(P = 0.006)。治疗后即刻的平均热损伤为20微米。

结论

使用上述参数进行4次照射的二氧化碳/铒:钇铝石榴石激光,其改善程度与其他高能、短脉冲二氧化碳激光皮肤磨削术相似。

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