Jeong J T, Kye Y C
Department of Dermatology, Korea University Anam Hospital, Seoul, Korea.
Dermatol Surg. 2001 Feb;27(2):107-10. doi: 10.1046/j.1524-4725.2001.00201.x.
Conventional short-pulsed Er:YAG lasers show less effective hemostasis and weak photothermal damage on papillary dermis. Recently, newer long-pulsed Er:YAG laser systems has been developed.
To evaluate the clinical and histologic effects of long-pulsed Er:YAG laser resurfacing for pitted facial acne scars.
Thirty-five patients with pitted facial acne scars were treated with a long-pulsed Er:YAG laser. All patients had Fitzpatrick skin phototypes III-V. A pulsed Er:YAG laser with a 5 mm handpiece at a setting of 7.0-7.5 J/cm2 with a 10-msec pulse duration was used. The laser was fired at 5 Hz, with four to five passes. In 28 patients, the results of laser treatment were evaluated for the degree of clinical improvement, duration of erythema, pigmentary change, and any adverse events at 2 weeks, 1 month, and 3 months. In seven patients, skin biopsy specimens were obtained at the following intervals: immediately, 1 week, 2 weeks, 4 weeks, and 8 weeks postoperatively for histologic examination.
The results of long-pulsed Er:YAG laser resurfacing for pitted facial acne scars were excellent in 10 patients (36%), good in 16 patients (57%), and fair in 2 patients (7%). Erythema occurred in all patients after laser treatment and lasted longer than 3 months in 15 patients (54%). Postinflammatory hyperpigmentation occurred in 8 patients (29%). But the pigmentation faded or disappeared within 3 months. One patient (4%) experienced mild hypopigmentation. Pruritic symptoms that required medical intervention occurred in 16 patients (57%). Mild to moderate postoperative acne flare-up occurred in 8 patients (29%). No other adverse effects such as scarring, bacterial infection, or contact dermatitis were observed.
In conclusion, resurfacing with a long-pulsed Er:YAG laser is a safe and very effective treatment modality for pitted facial acne scars.
传统的短脉冲铒:钇铝石榴石激光在止血方面效果较差,对乳头层真皮的光热损伤较弱。最近,新型长脉冲铒:钇铝石榴石激光系统已被开发出来。
评估长脉冲铒:钇铝石榴石激光磨皮术治疗面部凹陷性痤疮瘢痕的临床和组织学效果。
35例面部凹陷性痤疮瘢痕患者接受长脉冲铒:钇铝石榴石激光治疗。所有患者的皮肤 Fitzpatrick 分型均为 III - V 型。使用配备 5 mm 手柄的脉冲铒:钇铝石榴石激光,能量设置为 7.0 - 7.5 J/cm²,脉冲持续时间为 10 毫秒。激光以 5 Hz 的频率发射,进行四至五次扫描。28 例患者在术后 2 周、1 个月和 3 个月时评估激光治疗的临床改善程度、红斑持续时间、色素变化及任何不良事件。7 例患者在术后即刻、1 周、2 周、4 周和 8 周获取皮肤活检标本进行组织学检查。
长脉冲铒:钇铝石榴石激光磨皮术治疗面部凹陷性痤疮瘢痕的效果,10 例患者(36%)为优,16 例患者(57%)为良,2 例患者(7%)为中。所有患者激光治疗后均出现红斑,15 例患者(54%)红斑持续超过 3 个月。8 例患者(29%)出现炎症后色素沉着。但色素沉着在 3 个月内消退或消失。1 例患者(4%)出现轻度色素减退。16 例患者(57%)出现需要药物干预的瘙痒症状。8 例患者(29%)出现轻度至中度术后痤疮复发。未观察到其他不良反应,如瘢痕形成、细菌感染或接触性皮炎。
总之,长脉冲铒:钇铝石榴石激光磨皮术是治疗面部凹陷性痤疮瘢痕的一种安全且非常有效的治疗方式。