Bloom S R, Mitznegg P, Bryant M G
Scand J Gastroenterol Suppl. 1976;39:47-52.
A specific radioimmunoassay has been developed for human plasma motilin. No cross reaction was seen with other gut hormones and only a single major peak of motilin immunoreactivity was found in plasma and gut extracts after gel chromatography. The motilin content of the human duodenum was 165.7+/-15.9 pmol/g wet weight and jejunum 37.5+/-2.8 pmol/g with negligible amounts in the rest of the gut. Fasting plasma motilin concentrations in 100 healthy subjects ranged from less than 5 to 300 pmol/l (mean 72 pmol/l).
已开发出一种针对人血浆胃动素的特异性放射免疫测定法。未观察到与其他肠道激素的交叉反应，并且在凝胶色谱后，血浆和肠道提取物中仅发现一个主要的胃动素免疫反应峰。人十二指肠的胃动素含量为165.7±15.9 pmol/g湿重，空肠为37.5±2.8 pmol/g，肠道其他部位的含量可忽略不计。100名健康受试者的空腹血浆胃动素浓度范围为小于5至300 pmol/l（平均72 pmol/l）。
