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应用耳部氢化可的松新霉素滴耳液后出现多形红斑。

Erythema multiforme after application of aural Gentisone HC drops.

作者信息

Siddiq M A

机构信息

Department of Otolaryngology, Leicester Royal Infirmary, UK.

出版信息

J Laryngol Otol. 1999 Nov;113(11):1002-3. doi: 10.1017/s0022215100145827.

DOI:10.1017/s0022215100145827
PMID:10696380
Abstract

Erythema multiforme is an uncommon acute self-limiting condition characterized by mucocutaneous lesions of varying severity with a variable pattern of recurrence. This is a case of a four-year-old girl who developed erythema multiforme secondary to topical aural application of Gentisone HC drops (hydrocortisone acetate one per cent, gentamicin 0.3 per cent (as sulphate)) prescribed as a treatment for otorrhoea following grommet insertion. The clinical features are described and the literature reviewed. To my knowledge, this is the first reported case in the literature, of erythema multiforme secondary to a topical aminoglycoside/steroid preparation.

摘要

多形红斑是一种罕见的急性自限性疾病,其特征为严重程度各异的黏膜皮肤损害,复发模式不一。这是一例4岁女童的病例,她在鼓膜置管术后因耳部局部应用庚酸氢化可的松滴眼液(1%醋酸氢化可的松,0.3%庆大霉素(硫酸盐))治疗耳漏而继发多形红斑。本文描述了其临床特征并对相关文献进行了综述。据我所知,这是文献中首次报道的因局部应用氨基糖苷类/类固醇制剂继发多形红斑的病例。

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