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心脏组织在密封边界处极化的机制。

Mechanism for polarisation of cardiac tissue at a sealed boundary.

作者信息

Roth B J

机构信息

Department of Physics, Oakland University, Rochester, MI 48309, USA.

出版信息

Med Biol Eng Comput. 1999 Jul;37(4):523-5. doi: 10.1007/BF02513340.

Abstract

If current is flowing in cardiac tissue, and if the myocardial fibres approach a sealed boundary at an angle, then the tissue within a few length constants of the boundary is polarised. This polarisation occurs when the cardiac tissue has different anisotropy ratios in the intracellular and extracellular spaces. This new mechanism of tissue polarisation is demonstrated using a simple, analytical model, and it is shown quantitatively that this polarisation can be nearly as large as that occurring near an electrode.

摘要

如果电流在心脏组织中流动,并且心肌纤维以一定角度接近封闭边界,那么在边界几个长度常数范围内的组织就会发生极化。当心脏组织在细胞内和细胞外空间具有不同的各向异性比率时,就会出现这种极化现象。利用一个简单的分析模型证明了这种新的组织极化机制,并且定量显示这种极化几乎可以与电极附近发生的极化一样大。

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