Seifert S A, Bronstein A C, McGuire T
Rocky Mountain Poison and Drug Center, Denver, Colorado, USA.
J Toxicol Clin Toxicol. 2000;38(1):55-7. doi: 10.1081/clt-100100917.
To report a massive, 100 g ibuprofen ingestion in an adolescent, with survival.
The patient developed coma, metabolic acidosis, and mild thrombocytopenia, but improved rapidly with supportive care. Renal function remained normal and no gastrointestinal bleeding occurred.
Massive ingestion of ibuprofen may result in a variable picture with some elements of significant toxicity, but supportive care usually results in survival without sequelae.
报告一名青少年大量摄入100克布洛芬并存活的病例。
该患者出现昏迷、代谢性酸中毒和轻度血小板减少，但通过支持治疗迅速好转。肾功能保持正常，未发生胃肠道出血。
大量摄入布洛芬可能导致表现各异的情况，其中一些具有明显的毒性特征，但支持治疗通常可使患者存活且无后遗症。
