Tinkanen H, Kujansuu E
Department of Obstetrics and Gynecology, Tampere University Hospital, Finland.
Acta Obstet Gynecol Scand. 2000 Feb;79(2):119-22. doi: 10.1034/j.1600-0412.2000.079002119.x.
The objective of the study was to establish whether operative treatment of recurrent ovarian endometriosis improves the prognosis of in vitro fertilization.
A retrospective analysis of one hundred endometriosis patients admitted to Tampere University Hospital for IVF treatment. Forty-five patients had an ovarian endometrioma during IVF treatment, 36 of the cases being recurrences after a previous operation. Fifty-five patients had ovarian endometriomas operated without recurrence. The patient groups with or without endometriosis did not differ in age, duration of infertility, sperm parameters, amount of gonadotropins required per oocyte and number of retrieved oocytes.
The patients with ovarian endometriosis had more embryos (mean 3.9) than women without endometriomas (mean 2.8) (p<0.05) and the respective pregnancy rates per IVF cycle were 38% and 22%. Patients with endometriomas had a live birth rate of 27% compared with 20% in women with no endometriomas.
The presence of a small endometrioma does not reduce the success of IVF treatment.
本研究的目的是确定复发性卵巢子宫内膜异位症的手术治疗是否能改善体外受精的预后。
对坦佩雷大学医院收治的100例接受体外受精治疗的子宫内膜异位症患者进行回顾性分析。45例患者在体外受精治疗期间患有卵巢子宫内膜异位囊肿，其中36例为先前手术后复发。55例患者接受了无复发的卵巢子宫内膜异位囊肿手术。有或无子宫内膜异位症的患者组在年龄、不孕持续时间、精子参数、每个卵母细胞所需促性腺激素量和回收卵母细胞数量方面无差异。
患有卵巢子宫内膜异位症的患者比没有子宫内膜异位囊肿的女性有更多的胚胎（平均3.9个）（p<0.05），每个体外受精周期的相应妊娠率分别为38%和22%。有子宫内膜异位囊肿的患者活产率为27%，而没有子宫内膜异位囊肿的女性为20%。
小的子宫内膜异位囊肿的存在不会降低体外受精治疗的成功率。
