Rubinstein R Y, Baredes S, Caputo J, Galati L, Schwartz R A
Section of Otolaryngology-Head and Neck Surgery, University of Medicine and Dentistry of New Jersey, Newark, USA.
Ear Nose Throat J. 2000 Feb;79(2):96-7, 100-1.
Cutaneous metastatic disease is a prognostically important diagnosis. We report the case of a 64-year-old man who had an uncommon histologic type of lung cancer--a large cell undifferentiated carcinoma, which was metastatic to the skin of the nose. The relative frequency of cutaneous metastasis is similar to that of primary cancers. Cutaneous disease as the first sign of metastasis is most often seen in cancer of the lung. However, its appearance as a large tumor on the nose, which was observed in this case, is unusual.
皮肤转移性疾病是一种具有重要预后意义的诊断。我们报告一例64岁男性病例，其患有一种罕见组织学类型的肺癌——大细胞未分化癌，该癌症转移至鼻部皮肤。皮肤转移的相对发生率与原发性癌症相似。皮肤病变作为转移的首发症状最常见于肺癌。然而，如本病例中所观察到的，其表现为鼻部的巨大肿瘤并不常见。
