Dörfler P, Puls I, Schliesser M, Mäurer M, Becker G
Department of Neurology, Bayerische, Julius Maximilians University, Würzburg, Germany.
J Cereb Blood Flow Metab. 2000 Feb;20(2):269-71. doi: 10.1097/00004647-200002000-00007.
Measurement of global cerebral blood flow (CBF) using extracranial duplex sonography has been described, but normal values are still lacking. In 85 healthy adults (median age 43.4 years, range 20 to 80 years), CBF was determined by duplex sonographic examination of both internal carotid arteries and vertebral arteries. The mean global CBF was 630+/-97 mL/min. Global CBF declined with age; sex did not influence the total CBF. When measurements were repeated, the intraindividual variability was low. This noninvasive sonographic measurement of CBF is reproducible, and values correspond closely to those obtained with positron emission tomography and magnetic resonance imaging.
已描述了使用颅外双功超声测量全脑血流量（CBF）的方法，但仍缺乏正常值。在85名健康成年人（年龄中位数43.4岁，范围20至80岁）中，通过对双侧颈内动脉和椎动脉进行双功超声检查来测定CBF。全脑平均CBF为630±97 mL/分钟。全脑CBF随年龄下降；性别不影响总CBF。重复测量时，个体内变异性较低。这种CBF的无创超声测量具有可重复性，其值与正电子发射断层扫描和磁共振成像所获得的值密切对应。
