[一例对低剂量顺铂/5-氟尿嘧啶联合化疗有反应的胃癌肝转移病例]
[A case of gastric cancer with liver metastasis responding to low-dose CDDP/5-FU combination chemotherapy].
作者信息
Iwatani Y, Ohno M, Kamigaki T, Nakamura T, Suzuki Y, Iwasaki T, Sinmaru H, Hirata K, Kuroda Y
机构信息
First Dept. of Surgery, Kobe University School of Medicine.
出版信息
Gan To Kagaku Ryoho. 2000 Feb;27(2):277-80.
We reported a case of a 62-year-old female with gastric cancer accompanied by liver, Virchow and paraaortic lymph nodes, and bone metastasis (taken low-dose cisplatin (CDDP)/5-fluorouracil (5-FU) combination chemotherapy). CDDP (10 mg/body/day) was injected on 1-5 days i.v. and 5-FU (500 mg/body/day) was injected i.v. continuously on 1-7 days. This treatment cycle was repeated for 4 weeks. After 4 cycles, liver metastasis disappeared without severe side effects. Primary lesion and Virchow's lymph nodes metastasis were reduced. However, bone and paraaortic lymph node metastasis showed no response. It was considered that low-dose CDDP/5-FU combination chemotherapy was effective for liver and lymph nodes metastasis of gastric cancer in this case.
我们报告了一例62岁女性胃癌患者，伴有肝、魏尔啸淋巴结和主动脉旁淋巴结转移以及骨转移（接受低剂量顺铂（CDDP）/5-氟尿嘧啶（5-FU）联合化疗）。顺铂（10mg/体/天）于第1至5天静脉注射，5-氟尿嘧啶（500mg/体/天）于第1至7天持续静脉注射。该治疗周期重复4周。4个周期后，肝转移消失且无严重副作用。原发灶和魏尔啸淋巴结转移有所减轻。然而，骨和主动脉旁淋巴结转移无反应。认为低剂量顺铂/5-氟尿嘧啶联合化疗对该病例的胃癌肝转移和淋巴结转移有效。
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