单卵双胞胎中的双侧近黄斑部毛细血管扩张症

Bilateral juxtafoveolar telangiectasis in monozygotic twins.

作者信息

Menchini U, Virgili G, Bandello F, Malara C, Rapizzi E, Lanzetta P

机构信息

Department of Ophthalmology, University of Udine, Italy.

出版信息

Am J Ophthalmol. 2000 Mar;129(3):401-3. doi: 10.1016/s0002-9394(99)00380-3.

DOI:10.1016/s0002-9394(99)00380-3

PMID:10704569

Abstract

PURPOSE

To report the clinical and angiographic features of two monozygotic twins affected by bilateral group 2 idiopathic juxtafoveolar telangiectasis.

METHOD

Case reports.

RESULTS

Two 64-year-old women, who were identical twins, were suffering from visual loss. One twin had suffered from visual loss for 1 year and had a visual acuity of 20/25 in both eyes, and the other twin had suffered for 2 years and had a visual acuity of 20/30 in both eyes. Fluorescein angiography disclosed similar fundus features. An analogous area of capillary telangiectasis and leakage was observed in the right macula, where no intraretinal pigment was seen; the left macula showed a similar amount of intraretinal pigment associated with tiny right-angle venules and minimal leakage.

CONCLUSION

This observation raises the issue of genetic influences in the pathogenesis of this disease.

摘要

目的

报告两例受双侧2型特发性黄斑旁毛细血管扩张症影响的单卵双胞胎的临床及血管造影特征。

方法

病例报告。

结果

两名64岁的同卵双胞胎女性均有视力下降。其中一名双胞胎视力下降1年，双眼视力为20/25，另一名双胞胎视力下降2年，双眼视力为20/30。荧光素血管造影显示眼底特征相似。在右黄斑区观察到类似的毛细血管扩张和渗漏区域，未见视网膜内色素；左黄斑区显示有类似数量的视网膜内色素，伴有微小的直角小静脉和少量渗漏。