Petersen R, Thomsen J F, Jørgensen N K, Mikkelsen S
Department of Occupational Medicine, Glostrup Hospital, University of Copenhagen, Denmark.
Occup Environ Med. 2000 Feb;57(2):140-2. doi: 10.1136/oem.57.2.140.
For 8 years chromium in serum and urine has been followed up in a former plasma cutter of stainless steel who was exposed to airborne dust and fumes containing chromium during this work. After the first examination for serum chromium the exposure ended. Serum chromium concentration has been measured seven times during the period and was initially very high and has subsequently dropped slowly. The half life was 40 months in serum. Urinary chromium has been measured five times. The half life was 129 months in urine. The study shows that exposure to airborne dust and fumes containing chromium may cause accumulation of chromium in the body, and that when exposure ends, elimination of chromium is very slow. Previous studies suggest that chromium mainly accumulates in the lungs.
8年来,我们对一名曾从事不锈钢等离子切割工作的工人进行了血清和尿液中铬含量的跟踪调查。在此工作期间,他暴露于含有铬的空气尘埃和烟雾中。首次检测血清铬后,暴露停止。在此期间,血清铬浓度共测量了7次,最初非常高,随后缓慢下降。血清中铬的半衰期为40个月。尿液铬测量了5次。尿液中铬的半衰期为129个月。该研究表明,暴露于含有铬的空气尘埃和烟雾中可能会导致铬在体内蓄积,并且当暴露停止时,铬的消除非常缓慢。先前的研究表明,铬主要蓄积在肺部。