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心肺移植受者严重胃轻瘫的外科治疗

The surgical management of severe gastroparesis in heart/lung transplant recipients.

作者信息

Akindipe O A, Faul J L, Vierra M A, Triadafilopoulos G, Theodore J

机构信息

Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA 94305-5407, USA.

出版信息

Chest. 2000 Mar;117(3):907-10. doi: 10.1378/chest.117.3.907.

Abstract

This article describes the use of gastric bypass surgery for severe gastroparesis in two lung transplant recipients. In addition to feeding intolerance, both our patients suffered from severe erosive esophagitis, transfusion-dependent upper GI hemorrhage, and recurrent aspiration pneumonia. They responded poorly to promotility agents and were eventually treated with Roux-en-Y esophagojejunostomy-one patient with subtotal gastrectomy, and one with gastric bypass without distal gastric resection. Both cases were improved by surgery. Early surgical referral may be indicated in the management of lung transplant recipients with severe symptomatic gastroparesis in whom medical management has failed. On the basis of our experience, gastric bypass with esophagojejunostomy is a worthwhile option in lung transplant recipients with severe gastroparesis.

摘要

本文描述了胃旁路手术在两名肺移植受者严重胃轻瘫治疗中的应用。除了喂养不耐受外,我们的两名患者均患有严重的糜烂性食管炎、依赖输血的上消化道出血以及复发性吸入性肺炎。他们对促动力药物反应不佳,最终接受了Roux-en-Y食管空肠吻合术治疗——一名患者行胃次全切除术,另一名患者行胃旁路术且未行远端胃切除术。两例患者术后均有改善。对于内科治疗失败的有严重症状性胃轻瘫的肺移植受者,早期手术转诊可能是必要的。基于我们的经验,食管空肠吻合术式的胃旁路手术对于患有严重胃轻瘫的肺移植受者是一个值得考虑的选择。

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