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无症状受试者中衰老和吸烟与肺部薄层CT空气潴留的相关性。

Correlation of aging and smoking with air trapping at thin-section CT of the lung in asymptomatic subjects.

作者信息

Lee K W, Chung S Y, Yang I, Lee Y, Ko E Y, Park M J

机构信息

Department of Radiology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, South Korea.

出版信息

Radiology. 2000 Mar;214(3):831-6. doi: 10.1148/radiology.214.3.r00mr05831.

DOI:10.1148/radiology.214.3.r00mr05831
PMID:10715053
Abstract

PURPOSE

To assess the frequency and degree of air trapping at thin-section computed tomography (CT) of the lung in relation to age and smoking history in asymptomatic subjects.

MATERIALS AND METHODS

Thin-section CT of the lung was performed prospectively at end inspiration and end expiration in 82 subjects (27 smokers, 55 nonsmokers) without any history of pulmonary diseases and without present pulmonary symptoms. The frequency and degree of air trapping were evaluated according to age and smoking status.

RESULTS

The overall frequency of air trapping was 52% (43 of 82 subjects, kappa = 0.72). Air trapping was found in three of 13 (23%), seven of 17 (41%), nine of 18 (50%), 11 of 17 (65%), and 13 of 17 (76%) subjects aged 21-30, 31-40, 41-50, 51-60, and greater than or equal to 61 years, respectively. The frequency of air trapping increased with age (P < .05). The degree of air trapping had a significant correlation with age (r = 0.523, P < .001) and was higher in smokers with a smoking history of more than 10 pack-years (P < .05).

CONCLUSION

Air trapping was found in approximately 50% of asymptomatic subjects. The frequency of air trapping increased with age, and its severity increased with age and smoking.

摘要

目的

评估无症状受试者中,肺部薄层计算机断层扫描(CT)上空气潴留的频率和程度与年龄及吸烟史的关系。

材料与方法

对82名无肺部疾病史且无当前肺部症状的受试者(27名吸烟者,55名非吸烟者)在吸气末和呼气末进行前瞻性肺部薄层CT检查。根据年龄和吸烟状况评估空气潴留的频率和程度。

结果

空气潴留的总体频率为52%(82名受试者中的43名,kappa = 0.72)。在年龄分别为21 - 30岁、31 - 40岁、41 - 50岁、51 - 60岁和大于或等于61岁的受试者中,空气潴留的发生率分别为13名中的3名(23%)、17名中的7名(41%)、18名中的9名(50%)、17名中的11名(65%)和17名中的13名(76%)。空气潴留的频率随年龄增加而升高(P <.05)。空气潴留的程度与年龄显著相关(r = 0.523,P <.001),且在吸烟史超过10包年的吸烟者中更高(P <.05)。

结论

约50%的无症状受试者存在空气潴留。空气潴留的频率随年龄增加而升高,其严重程度随年龄和吸烟情况增加。

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