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儿童感染的金氏金杆菌

Kingella kingae infections in children.

作者信息

Dodman T, Robson J, Pincus D

机构信息

Department of Paediatrics, Gold Coast Hospital, Southport, Queensland, Australia.

出版信息

J Paediatr Child Health. 2000 Feb;36(1):87-90. doi: 10.1046/j.1440-1754.2000.00447.x.

Abstract

OBJECTIVE

To increase awareness of Kingella kingae infections in children by presenting four cases seen at the Gold Coast Hospital, Southport, Queensland, and reviewing the literature.

METHODOLOGY

Records of the four cases were reviewed and relevant information described. A MEDLINE search of the English literature from 1983 to 1998 was conducted.

RESULTS

Osteoarticular infections are the commonest type of invasive paediatric infection but bacteraemia and endocarditis also occur. Isolation of the organism is difficult but inoculation of the specimen into enriched blood culture systems improves the recovery rate. The majority of isolates are sensitive to beta-lactam antibiotics but resistance has been described.

CONCLUSIONS

Kingella kingae infections in children are more common than previously recognized. The organism should be actively sought in any child with suspected osteoarticular infections. Recommended empiric therapy is a third generation cephalosporin until susceptibility to penicillin is confirmed.

摘要

目的

通过介绍在昆士兰州南港黄金海岸医院所见的4例病例并复习相关文献,提高对儿童金氏金杆菌感染的认识。

方法

回顾了这4例病例的记录并描述了相关信息。对1983年至1998年的英文文献进行了医学文献数据库(MEDLINE)检索。

结果

骨关节炎感染是侵袭性儿科感染最常见的类型,但也会发生菌血症和心内膜炎。该病原体的分离困难,但将标本接种到增菌血培养系统中可提高回收率。大多数分离株对β-内酰胺类抗生素敏感,但也有耐药的报道。

结论

儿童金氏金杆菌感染比以前认为的更为常见。对于任何疑似骨关节炎感染的儿童,都应积极寻找该病原体。推荐的经验性治疗是使用第三代头孢菌素,直至确认对青霉素敏感。

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