Lacour M, Duarte M, Beutler A, Auckenthaler R, Suter S
Clinique Universitaire de Pédiatrie, Geneva, Switzerland.
Eur J Pediatr. 1991 Jul;150(9):612-8. doi: 10.1007/BF02072618.
By the description of two cases of osteoarticular infections due to Kingella kingae in two young children we wish to draw the attention of clinicians to invasive infections due to this micro-organism. Since its biological characterization in 1976, K. kingae has been increasingly reported as a human pathogen. Most common presentations are endocarditis, bacteraemia, septic arthritis, osteomyelitis and spondylodiscitis. Interestingly, osteorticular involvement is largely predominant in previously healthy children. From the literature, we reviewed 51 cases of K. kingae bone and joint infections, representing 23 cases of septic arthritis, 17 of osteomyelitis and 11 spondylodiscitis. Of the cases 88% occurred in children below 5 years of age and in all cases only one bone or joint was involved. An underlying disorder could be found in only 4 patients. Since these infections have a favourable outcome with intravenous antibiotic treatment, proper isolation and identification of K. kingae is essential.
通过描述两名幼儿因金氏金杆菌引起的骨关节炎感染病例,我们希望引起临床医生对这种微生物所致侵袭性感染的关注。自1976年对其生物学特性进行描述以来,金氏金杆菌作为人类病原体的报道日益增多。最常见的表现为心内膜炎、菌血症、化脓性关节炎、骨髓炎和脊椎椎间盘炎。有趣的是,在既往健康的儿童中,骨和关节受累在很大程度上占主导地位。我们从文献中回顾了51例金氏金杆菌骨和关节感染病例,其中23例为化脓性关节炎,17例为骨髓炎,11例为脊椎椎间盘炎。这些病例中88%发生在5岁以下儿童,且所有病例均仅累及一个骨或关节。仅在4例患者中发现有潜在疾病。由于这些感染经静脉抗生素治疗预后良好,因此正确分离和鉴定金氏金杆菌至关重要。